2025 BiLevel & BiPAP Machine Buying Guide

DirectHomeMedical’s 2025 BiPAP & BiLevel Machine Buying Guide makes choosing your ideal sleep therapy device simple. Our expert insights and easy-to-follow comparison chart highlight key features--pressure modes, humidification, sound level, weight, connectivity, and more--so you can quickly find the model that fits your comfort needs and prescription.

What Makes BiPAP Different?
BiPAP (BiLevel Positive Airway Pressure) machines provide two pressure levels--one for inhaling and a lower one for exhaling--creating a more natural breathing rhythm than standard CPAP therapy. This dual-pressure design is ideal for users who need higher pressure support or experience complex sleep apnea, helping you breathe easier and sleep deeper every night.

(BiPAP Machines are great; but they're not for everyone. If your doctor has prescribed CPAP therapy, click here to check out our CPAP Machine Buying Guide.)

Types of BiPAP Machines
Today’s BiPAP machines offer smart technology and personalized comfort. Choose from fixed-pressure BiLevel models for consistent therapy or Auto BiLevel systems that automatically adjust to your breathing patterns. For your convenience, all of the machines in our buying guide feature both BiPAP and Auto-BiPAP modes. If your prescription calls for more advanced therapy modes like "BiPAP ASV" or "BiPAP ST" please get in touch with our Care Team to discuss available options.

Key Features to Compare
When choosing a sleep therapy device, it’s important to look beyond the basics and focus on features that impact comfort, performance, and convenience. Most modern BiLevels have similar pressure ranges; but comfort-enhancing features--like exhalation relief, ramp, heated humidifiers, and heated tubing options--can vary from unit to unit; and data tracking and Bluetooth connectivity may be a factor if you need to provide compliance data to your doctor or employer or if you simply want to be able to monitor your sleep therapy success

FAA Approval & Travel Readiness
Every BiPAP machine we sell at DirectHomeMedical is FAA-approved for in-flight use, making it easy to maintain your sleep therapy routine wherever you go. Whether you’re traveling for business, vacation, or overnight trips, your BiPAP can safely accompany you on the plane. We recommend packing all necessary accessories--including power cords, adapters, and extra filters or batteries--in your carry-on for convenience. Always bring a copy of your prescription for airport security, and contact your airline prior to travel to ensure you meet their requirements for carriage. With a little preparation, you can enjoy restful, uninterrupted sleep no matter where your travels take you.

Luna G3 Auto BiPAP
Luna G3 25A Auto-BiPAP
AirCurve 10 Auto-BiLevel
AirCurve 10 VAUTO
AirCurve 11 VAUTO
AirCurve 11 VAUTO
LEARN MORE
$1499
Risk Free Trial
LEARN MORE
$1776
Risk Free Trial
LEARN MORE
$1796
Risk Free Trial
star rating1 Review star rating2 Reviews star rating1 Review
DIMENSIONS & WEIGHT
4.00 Lbs 2.75 Lbs 2.70 Lbs
10.4 x 5.7 x 4.5 Inches 4.6 x 10 x 5.9 Inches 3.7 x 10.2 x 5.5 Inches
OPERATING SOUND LEVELS
≤ 26 dBA ≤ 27 dBA ≤ 27 dBA
THERAPY MODES
CPAP CPAP CPAP
Auto-CPAP Auto-CPAP Auto-CPAP
BiLevel VPAP / BiLevel VPAP / BiLevel
Auto-BiLevel Auto-BiLevel Auto-BiLevel
FILTERS
Disposable or Reusable Disposable Disposable
THERAPY COMPLIANCE TRACKING APP
React Health Plus App MyAir App MyAir App
FAA APPROVED FOR USE ON FLIGHTS
Yes Yes Yes
UNIVERSAL MASK COMPATIBILITY
Yes Yes Yes
FEATURES
Pressure Range
4-25 CM 4-25 CM 4-25 CM
User Adjustable Ramp
Up to 45 Min Up to 45 Min Up to 45 Min
Automatic Altitude Adjustment
Not Specified Up to 8,500 Feet Up to 9,870 Feet
Expiratory Pressure Relief Technology
RESlex EPR EPR
Compatible With Oxygen Therapy
Yes Up to 15 LPM Up to 15 LPM
Humidification Options
Internal Heated Internal Heated Internal Heated
360 mL Chamber 380 mL Chamber 380 mL Chamber
Heated Tubing Options (Rainout Reduction)
React Heated ClimateLineAir ClimateLineAir
Standard Tubing Compatibility
Yes Yes Yes
POWER OPTIONS
Wall (AC) Power & Cord Weight
Universal AC Universal AC Universal AC
0.8 Lbs 1.3 Lbs 0.9 Lbs
Mobile (DC) Power & Cord Weight
Optional DC Cord Optional DC Cord None
0.85 Lbs 1.69 Lbs -
Battery Power, Run Times & Weight
Third Party Only Third Party Only Third Party Only
DEVICE WARRANTY
2 Years 2 Years 2 Years
MANUFACTURING DETAILS
React
Made in China
Resmed
Made in Australia
Resmed
Made in Australia

NOTES: Dimensions and weight are approximations. Typical sound levels for portable oxygen concentrators are measured at a setting of 2. Typical sound levels for home oxygen concentrators are measured at the highest liter flow. Typical sound levels for sleep therapy devices are measured at average therapy settings with an overall accuracy of +/- 2dBA. In all cases an adapter or special tubing is required when using CPAP with an oxygen concentrator. FAA Approval indicated for use on all Commercial Flights departing from or arriving in the US. Contact your airline for any specific requirements. Review manufacturer's specifications and documentation for additional information on product specifications and features.